Blar i NTNU Open på forfatter "Ravlo, Erlend"

Viser treff 1-8 av 8

    • Antiviral Immunoglobulins of Chicken Egg Yolk for Potential Prevention of SARS-CoV-2 Infection 

      Ravlo, Erlend; Evensen, Lasse; Sanson, Gorm; Hildonen, Siri; Ianevski, Aleksandr; Skjervold, Per Olav; Ji, Ping; Wang, Wei; Kaarbø, Mari; Kaynova, Gerda Dominyka; Kainov, Denis; Bjørås, Magnar (Peer reviewed; Journal article, 2022)
      Background: Some viruses cause outbreaks, which require immediate attention. Neutralizing antibodies could be developed for viral outbreak management. However, the development of monoclonal antibodies is often long, ...

    • Boosted production of antibodies that neutralized different SARS-CoV-2 variants in a COVID-19 convalescent following messenger RNA vaccination - a case study. 

      Fenstad, Mona H.; Ravlo, Erlend; Ianevski, Aleksandr; Starheim, Eirin Johannessen; Wang, Wei; Lysvand, Hilde; Smura, Teemu; Ji, Ping; Kivi, Gaily; Voolaid, Maia-Liisa; Plaan, Kati; Ustav, Mart; Ustav, Mart; Žusinaite, Eva; Tenson, Tanel; Kurg, Reet; Oksenych, Valentyn; Walstad, Kirsti; Nordbø, Svein Arne; Kaarbø, Mari; Ernits, Karin; Bjørås, Magnar; Kainov, Denis (Peer reviewed; Journal article, 2023)
      Vaccinated convalescents do not develop severe COVID-19 after infection with new SARS-CoV-2 variants. We questioned how messenger RNA (mRNA) vaccination of convalescents provides protection from emerging virus variants. ...

    • A fast, low-cost, robust and high-throughput method for viral nucleic acid isolation based on NAxtra magnetic nanoparticles 

      Ravlo, Erlend; Sousa, Mirta; Andresen, Lise Lima; Holberg-Petersen, Mona; Klundby, Ingvild; Aas, Per Arne; Hagen, Lars; Erlandsen, Sten Even; Fossum, Janne; Ali, Zeeshan; Sharma, Anuvansh; Ottesen, Vegar; Bandyopadhyay, Sulalit; Bjørås, Magnar (Peer reviewed; Journal article, 2023)
      The year of 2020 was profoundly marked by a global pandemic caused by a strain of coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19). ...

    • Generation of stem cell derived retinal organoids for the disease modeling and treatment of Retinitis Pigmentosa 

      Schjølberg, Jørn-Ove (Master thesis, 2021)
      The hereditary retinal disease Retinitis pigmentosa (RP) leads to loss of photoreceptor cells and is a significant cause of blindness, affecting over 2 million worldwide. This project focus on Retinitis pigmentosa type 11 ...

    • Mono- and combinational drug therapies for global viral pandemic preparedness 

      Ianevski, Aleksandr; Yao, Rouan; Simonsen, Ronja Meyer; Myhre, Vegard; Ravlo, Erlend; Kaynova, Gerda D.; Zusinaite, Eva; White, Judith M.; Polyak, Stephen J.; Oksenych, Valentyn; Windisch, Marc P.; Pan, Qiuwei; Lastauskienė, Eglė; Vitkauskienė, Astra; Matukevičius, Algimantas; Tenson, Tanel; Bjørås, Magnar; Kainov, Denis (Peer reviewed; Journal article, 2022)
      Broadly effective antiviral therapies must be developed to be ready for clinical trials, which should begin soon after the emergence of new life-threatening viruses. Here, we pave the way towards this goal by reviewing ...

    • NAxtra magnetic nanoparticles for low-cost, efficient isolation of mammalian DNA and RNA 

      Starheim, Eirin Johannessen; Ravlo, Erlend; Schjølberg, Jørn-Ove; Solvang, Vanessa; Wang, Wei; Scrimgeour, Nathan Robert; Manaf, Adeel; Erlandsen, Sten Even; Aas, Per Arne; Hagen, Lars; Sousa, Mirta; Bjørås, Magnar (Peer reviewed; Journal article, 2023)
      A cost-effective, viral nucleic acid (NA) isolation kit based on NAxtra magnetic nanoparticles was developed at the Norwegian University of Science and Technology in response to the shortage of commercial kits for isolation ...

    • Screening of FDA-Approved Drugs Using a MERS-CoV Clinical Isolate from South Korea Identifies Potential Therapeutic Options for COVID-19 

      Meehyun, Ko; Chang, Soo Young; Byun, Soo Young; Ianevski, Aleksandr; Choi, Inhee; Pham Hung, Anne-Laure; Ravlo, Erlend; Wang, Wei; Bjørås, Magnar; Kainov, Denis; Shum, David; Min, Ji-Young; Windisch, Marc P. (Peer reviewed; Journal article, 2021)
      Therapeutic options for coronaviruses remain limited. To address this unmet medical need, we screened 5406 compounds, including United States Food and Drug Administration (FDA)-approved drugs and bioactives, for activity ...

    • Synergistic interferon-alpha-based combinations for treatment of sars-cov-2 and other viral infections 

      Ianevski, Aleksandr; Yao, Rouan; Zusinaite, Eva; Lello, Laura Sandra; Wang, Sainan; Jo, Eunji; Yang, Jaewon; Ravlo, Erlend; Wang, Wei; Lysvand, Hilde; Løseth, Kirsti; Oksenych, Valentyn; Tenson, Tanel; Windisch, Marc P.; Poranen, Minna M.; Nieminen, Anni I.; Nordbø, Svein Arne; Fenstad, Mona H.; Grødeland, Gunnveig; Aukrust, Pål; Trøseid, Marius; Kantele, Anu; Lastauskienė, Eglė; Vitkauskienė, Astra; Legrand, Nicolas; Merits, Andres; Bjørås, Magnar; Kainov, Denis (Journal article; Peer reviewed, 2021)
      Background: There is an urgent need for new antivirals with powerful therapeutic potential and tolerable side effects. Methods: Here, we tested the antiviral properties of interferons (IFNs), alone and with other drugs in ...